The characteristic relentless self-starvation behaviour seen in Anorexia Nervosa (AN) has been described as evidence of compulsivity, with increasing suggestion of parallels with addictive behaviour.This study used a Black High Rise Stove Pipe thematic qualitative analysis to investigate the parallels between compulsive behaviour in AN and Substanc
Abstract Rearrangements of the Pool Accessibility MLL (KMT2A) locus are associated with aggressive leukaemia of both myeloid and lymphoid lineages, that present profound therapeutic challenges in pediatric and adult patient populations.MLL-fusion genes resulting from these rearrangements function as driving oncogenes and have been the focus of rese
Although hormone therapy using estrogens plus progestogens (EPT) is effective for the management of menopausal symptoms (e.g., vasomotor symptoms and vulvar/vaginal atrophy) and prevention/treatment of postmenopausal osteoporosis, EPT is associated with safety and tolerability concerns.A new alternative to EPT is the tissue selective estrogen compl
Phenotypic plasticity allows individuals to respond to the selective forces of a new environment, followed by adaptive evolution.We do not know to what extent phenotypic plasticity allows thermal tolerance evolution in bacteria at the border of their Table physiological limits.We analyzed growth and reaction norms to temperature of strains of two b
The cytotoxicity of the venom of 25 species of Old World elapid snake was tested and compared with the morphological and behavioural adaptations of hooding and spitting.We determined that, contrary to previous assumptions, the venoms of spitting species are not consistently more cytotoxic than those of closely related non-spitting species.While thi